JunB anticorps
Aperçu rapide pour JunB anticorps (ABIN7126608)
Antigène
Voir toutes JunB (JUNB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
-
Réactivité croisée (Details)
- Human
-
Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
Immunogène
- Recombinant full-length human JUNB protein
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, K562 or MCF-7 cells.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
Agent conservateur
- Azide free
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
Date de péremption
- 24 months
-
-
- JunB (JUNB) (Jun B Proto-Oncogene (JUNB))
-
Autre désignation
- JUNB
-
Sujet
-
Activator protein 1 (AP1), Transcription factor junB, junB proto oncogene 9,JUNB
Cellular localisation: Nucleus -
Poids moléculaire
- 39kDa
-
ID gène
- 3726, 25292
-
UniProt
- P17275
Antigène
-